I think there's always one storm that comes through every year where I get waaaayyy too excited about things waaaayyy too far in advance. This one seems to fit the bill for me, hopefully I've gotten it out of my system for the rest of the year.
My primary concern Saturday with regards to squall line vs. supercell mode has to do with when the low-level shear will kick in, and whether or not it will be sufficiently backed relative to the upper-level flow. Regarding the latter, the surface/850mb low has a lobe extending to the northeast, unlike March 28, when it was oriented N/S along the lee side of the Rockies. This yields less backed flow in the low-levels north of the panhandles and a more linear shear profile with height, which given the meridional nature of the upper-level flow, will simply not work.
Between the KS border and I-40, the shear situation improves, but the timing is questionable, as initiation seems to be occurring before the low-level winds are able to back sufficiently given the SSW flow aloft. However, the storm motions in the region may be easterly enough for storms to be able to sustain themselves as separate entities long enough for the backing to kick in (which never happens further north).
South of I-40, things look more favorable for discrete activity, but south of Lubbock capping looks to be an issue. A notable difference between Saturday vs. 4/6/2001 is that the upper-level flow was much more backed further south.
However, there are many more similarities than differences between Saturday and 4/6/2001. And putting those things aside, just look at the progression of the 500mb trough axis from 00Z to 06Z. It travels from approx. El Paso, TX, to Altus, OK, in 6 hours! Given that there is about 500 miles of distance between those two points, that's an average speed of over 80mph. Sounds like things will certainly be going ridiculously linear at some point. As things stand now, I think there may be a narrow window of opportunity between 23Z and 02Z. Is it worth driving to Paducah? I don't know, I'll have to make that determination Sat. morning. Maybe it would be worth it just to get absolutely blasted by a derecho.

I was out chasing on 4/6/2001, and I wouldn't mind seeing another 100mph squall line--I've never seen anything move so fast in my life.