For tornadic supercells, we're often interested in low-level moisture. You can look at 2 m Tds, but it's best to look at Tds over some depth. For example, you may want to consider 2 m and 850 mb Tds, but picking a higher level depends upon the elevation of the area you're looking at. For example, you may want to look closer to 750 mb if you want to look for deeper moisture in eastern Colorado, and you'll want to look closer to 900 mb for an estimate of decent moisture depth if you're looking at Alabama. Using isentropic surfaces is actually probably best, since unsaturated air flows along isentropic surfaces, but that's probably a bit more complex than you want right now. Mets typically consider 75 - 100 mb inflow "layers" for convection, since you will want to see substantial moisture over a similar depth. It's not uncommon for rich moisture to be only 25-30 mb deep sometimes, which can make a chase forecast a bit more difficult. For example, 65 F surface Tds may grab one's attention, but if that moisture is only 25 mb deep, the potential for substantial supercells is typically quite reduced. Vertical soundings (RAOBs) are probably the best way to look for quality moisture depth.
The actual Tds that we look for in terms of supercell or tornado potential depends a lot on the time of year and location of the country. Realize that Td affects theta-e,which directly affects CAPE and can directly affect the intensity of updrafts. So, it's often thought that "higher is better" when it comes to low-level moisture. At any rate, getting back to the "rule of thumb"... This time of year, in the central and southern plains, upper-50 to low-60 F dewpoints can still yield substantial instability since mid-level temperatures are often quite cool this time of year. After we get into April and May, chasers often look for >60 F Tds, and we often want 67-75F Tds came June and July, when mid-level temperatures considerably warmer (on the whole). Note that this all addresses 2 m Tds, or dewpoint observations that you'll see on surface observations.
Remember, too, that the dewpoint temperature of a parcel decreases as it rises at a rate of ~2 C/km (~ 3.6 F / km, ~ 1.1 F / 1000 ft). Note this includes forced ascent as air moves up higher terrain. For example, a parcel that has a dewpoint temperature of 65 F near sea level (e.g. on the Corpus Cristi, TX, observation) will have a dewpoint temperature of 62 F at the elevation of Dodge City or 61 F at Amarillo.