I downgraded after several months of frustrations. I got most everything working GR3, photoshop (CS3, Premiere CS2 and before won't work as far as I know no support is planned, in fact when I first bought it, thier was not a single video editor that worked but, I think most vendors support it now). I got my Canon drivers finally working, casio elixim and a few other drivers never did work but, it had a card reader built in so problem solved. Had horrible time tethering under Vista. I finally got about 90% of things working when my VPN to work was not supported under Vista, so I downgraded to XP and rebuilt it and re-installed everything in about a day and a half, did'nt have a single issue installing a single app.
Due to the SATA drivers (for the hard disk) I had to load the SATA drivers from a floppy disk which the laptop did not have. Turns out XP only supports (from the boot CD ROM) only 3 models of USB floppy's, tracking down one of them took about a week. If you do decide to downgrade make sure you can get XP drivers for all of your hardware (the laptop) first, and if you have a SATA laptop and no floppy that might be a bit of an issue as well. Some BIOS's have an XP compatibillity mode (no clue- mine did'nt) which I hear helps, in some fashion.
I'd say in another year or so (or an SP or two) I might give it another try.