Scott Weberpal
EF5
My 99 Pontiac Bonneville has about 195k on it now. For the most part, it's been a pretty good car, though a broken starter and a melted hole in the upper intake (near the EGR "port" where, incidentally, GM opted to pipe through coolant, which resulted in coolant flooding the cylinders and rendering the engine unusable)
The intake manifold gasket is a problem with virtually every GM 3.8L V6 Series II, when I bought my Lumina LTZ a few years back, it was the first (and only) think I replaced. Cost me $50 and about 4 or so hours of my time, but definitely worth not having to replace the motor because a leaky gasket was allowing coolant into the cylinders.
Otherwise, the GM 3.8L V6 Series II will run forever. I had well over 250k on my Lumina when I sold it with no signs of the engine running rough or weaker than when I bought it. I loved getting 200+ HP and 30mph on the highway - it's probably the best power/mpg combination you'll find in any used vehicle.
My current car, a 1994 Honda Civic has about 220k on it now, and I fully plan on running it well over 300k miles.